Brown suggests giving a patient spiking intermittent fevers a fentanyl patch, and a doctor immediately shoots down the idea:
The doctor was referring to the fact that heat can interfere with the patch’s slow-release mechanism, causing it to “dump” a large dose of fentanyl all at once. Some patients wearing the patches have died, and some of those deaths were likely caused by a patient applying a heating pad, or because a patient had a fever.
I knew heating pads were a no-go with fentanyl (and, being under the age of 90, I don't tend to use them), but fever had never occurred to me. So it may be worth a call to nurse or pharmacist if you wear a patch and get hit with a heavy fever. You probably have enough tolerance to the narcotic to avoid actual danger -- but you might end up woozier than you'd like if the drug releases faster than normal because of the heat.
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